Cialis Vs Viagra Vs Levitra Vs Stendra – Which Is Comparatively Safer To Use?

Erectile dysfunction is a common occurrence in males. It is routinely treated with medications, such as Stendra (avanafil), Viagra (sildenafil), Cialis (tadalafil), and Levitra (vardenafil).

Regarding this subject, however, there are some distinct points of view. The purpose of utilizing Cialis and Viagra is for a man in being able to have a firm erection and maintain it.

According to the Urology Care Foundation, almost 35 million American men have trouble holding an erection and even achieving it in the first place.

When erectile dysfunction becomes a problem, most men turn to oral ED treatments. They often assist in resolving these problems.

The Food and Drug Administration has approved all of them. All of these drugs serve the same purpose, however, they might have some significant variances.

In this article, we shall be looking at how these medications work, who should get them, how to get them, dosage, interactions and a lot more.

How Do They Work?

PDE5 inhibitors, such as Stendra, Viagra, Cialis, and Levitra belong to a group of drugs known as PDE5 (phosphodiesterase type 5) inhibitors. These medications work by inhibiting the PDE5 enzyme.

These PDE5 inhibitors are medicines that all function in the same way. They aid in increased blood flow and muscular relaxation throughout the body.

Increased blood flow permits the blood to enter the penis more easily, which allows persons having ED to have a longer-lasting erection during their sexual activity. These medications work very swiftly, however, the exact timing depends on the drug.

They also increase the quantity of nitric oxide in your body which makes the muscles relax in your penis.

When the muscles are relaxed, blood could flow easily, thus allowing you to have an erection when you are stimulated. It also helps to maintain an erection long enough during intercourse.

Who Should Get Them?

Mental and physical health issues might contribute to erectile dysfunction. A doctor is going to discuss these issues as well as the lifestyle choices of an individual before prescribing these drugs.

Doctors might refuse to give the medications to someone who has a weak heart as it could make sexual activity quite risky.

Certain medications could heavily interact with erectile dysfunction medicines. You could learn more about those medications which might interact with these drugs in the sections below.

The medications Stendra, Cialis, Viagra, and Levitra are used to treat erectile dysfunction symptoms. If a person shows even one of these symptoms, a doctor shall diagnose ED:

  • Being able to have an erection but one which does not last very long enough during sexual intercourse.
  • Often being not able to have an erection.
  • Completely unable to have an erection.

Drug Interactions

Medicine interactions are always a possibility with every drug. As PDE5 inhibitors have a comparable effect on the body, Stendra, Cialis, Viagra, and Levitra might have similar side effects.

Anyone planning to use these medicines has to consult a doctor first. As the medications could interact with different drugs, or influence existing health issues of a person, they might not be suited for everyone.

According to a study, the following medications might increase the concentration of the PDE5 inhibitors in the body. Therefore, people should talk to their healthcare professionals before taking erectile dysfunction medications:

  • Ritonavir is an HIV protease inhibitor.
  • Ketoconazole, an anti-dandruff and antifungal agent.
  • The antibiotics are clarithromycin and azithromycin.

Cialis Interactions

An individual should not take Cialis with the following drugs:

  • An antibiotic known as Rifampin is a CYP3A4 inducer. They might prevent Cialis from working.
  • CYP3A4 inhibitors like ritonavir and ketoconazole, as might increase the impact.
  • Drugs for reducing blood pressure.
  • Alpha-blockers.
  • Nitrates.

Here is a governmental study on the same.

Viagra Interactions

Viagra might interact with the following drugs:

  • CYP4 inhibitors like erythromycin, ritonavir, and ketoconazole.
  • Drugs to lower blood pressure.
  • Alpha-blockers.
  • Nitrates like nitroglycerin.

Levitra Interactions

People should not take Levitra if they suffer from an irregular heartbeat and are using the following:

  • Drugs to reduce blood pressure.
  • Alpha-blockers.
  • Nitrates.

A doctor might adjust the dosage of a person if they have liver problems or are already using any one of the following:

  • The antibiotics erythromycin or clarithromycin.
  • The antifungal medications itraconazole or ketoconazole.
  • Atazanavir, indinavir, ritonavir, and saquinavir, are antiretroviral drugs that doctors use to prevent or treat HIV.

Stendra Interactions

Stendra should not be mixed with any CYP3A4 inhibitors like ritonavir or ketoconazole or nitrate medicines.

If you are using a mild CYP3A4 inhibitor like diltiazem, erythromycin, or amprenavir, and alpha-blockers, your doctor might adjust your dose.

People should have Stendra taking caution if they are taking these medications, as they could cause a drop in the blood pressure:

  • Alpha-blockers.
  • Alcohol.
  • Blood pressure-reducing drugs.

If you are taking a PDE5 inhibitor, never consume a lot of alcohol. Cialis could be less effective when combined with anti-seizure medications like phenobarbital and carbamazepine.

Consult your pharmacist or doctor for instructions on which medications are safer for you to use. In certain situations, using some medications might necessitate quitting the PDE5 inhibitors entirely.

In some situations, your healthcare professional or doctor might change your prescription dosage for reducing risks of drug interactions while taking PDE5 inhibitors.

Dosage

These drugs often come in a number of doses, ranging from 2 mg to 150 mg. All of them could be taken without or with food.

Taking Stendra, Viagra, and Levitra after a high-fat meal could slow absorption. Most of them might last 5 to 6 hours in your bloodstream. However, Cialis is an exception. It might last up to 35 hours in your bloodstream.

If you are taking these drugs, the time needed for a drug to stay in your body could be of utmost importance. Always take only one of these medications in a twenty-four-hour period.

Side Effects

The PDE-5 inhibitors Stendra, Viagra, Cialis, and Levitra have comparable though not identical side effects as they are chemically related but not completely identical.

It is important to know that while the side effects could be similar, certain medications might have different impacts on different people.

Eg, one medicine could induce a side effect whereas another might not. If a patient has an adverse reaction from one medicine, this is usually the rationale for switching to a completely different medication.

These are some of the prevalent side effects of PDE-5 inhibitors:

  • Symptoms like hot flashes.
  • Headaches.
  • Runny or a stuffy nose.
  • Dyspepsia or upset stomach.
  • Visual disturbances.
  • Muscle pain.

Some of the rare side effects are:

  • An erection that would not go away.
  • Sudden vision loss in both or one eye.
  • Hearing loss or sudden hearing decrease.

How Soon Do They Start Working?

Fast-acting drugs cannot stay in the body for a long time. This decreases the time throughout which they are effective.

Fast-acting drugs, such as sublingual vardenafil or Stendra are quite popular among individuals who are not able to plan their sex. Certain patients prefer to use long-acting drugs like Cialis, as its effect could last for many days.

Stendra, also known as avanafil, is one of the fastest-acting drugs for erectile dysfunction. In as little as 10 minutes, it starts working. It cannot, however, last for longer than 5-10 hours.

The onset of Levitra (vardenafil) and Viagra (sildenafil) is moderate. They come into effect in as short as 35-65 minutes. They could usually stay in the body for up to 5-10 hours.

Cialis (Tadalafil) takes 1 hour to start acting, but it could persist in your body for up to 2 days. Thus it earned its nickname as weekend medicine. Therefore, 1 pill, usually 15 or 30 mg, might be used every 3-5 days.

A different way to have Cialis is to consume a modest quantity every day, usually 2 or 3 mg. Viagra and Cialis are quite comparable in terms of efficacy.

How To Purchase Them?

A prescription is usually needed to obtain erectile dysfunction medicine. You could receive a prescription from health firms online or from your doctor. You might get your Stendra, Cialis, Viagra, and Levitra prescription at a drugstore.

If you have health insurance, do keep in mind that the price of your ED medication is usually not covered.

If you have, however, certain medical problems, your health plan might pay for the ED medicine if you have a prior authorization.

Any drug’s actual price is usually determined by your insurance plan and your pharmacy. Stendra, Viagra, Cialis, and Levitra generics could be half the price compared to their brand-name counterparts.

Before buying any erectile dysfunction drugs, talk to a healthcare expert or your doctor, especially if you are buying them through online mode.

Online erectile dysfunction drugs are usually not FDA authorized as they might contain hazardous or ineffective substances unless they are recommended by a doctor.

Which Is Comparatively Safer To Use?

Stendra’s effectiveness was shown to be the same as Viagra’s in a review of clinical research. Stendra also has fewer drug interactions and adverse effects, which makes it safer, according to the study.

Another evaluation of research indicated that Stendra is effective and safe, but predicted that the market position of Stendra could be ambiguous.

This is as each PDE5 inhibitor is comparable, and with Stendra’s exception, all of them are available in generic form. This saves people a huge amount of money.

Only your doctor could decide the most beneficial erectile dysfunction drug for you based on your medical history, condition, any medications you are taking.

Conclusion

Consult your doctor about Stendra, Viagra, Cialis, and Levitra if you have erectile dysfunction. If you are taking any additional prescription medications, tell your doctor.

Make sure to tell your doctor about any additional medical issues you might have. These medications have been shown to produce positive benefits, however, finding the correct one for you might take some patience and time.

You could try a different drug if one does not work and has undesirable side effects. It is also worth noting that none of these medications guarantees to stimulate your sexual desire.

To have an erection, the person shall require stimulation. It is possible that error and trial are the only way for finding the best medicine.

Working directly with your doctor might assist a person to keep track of the side effects and determine which drug would be best for them.

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